The best payment gateway for Shopify depends on your business location and preferences, but Shopify Payments is often the top choice. It’s fully integrated, easy to set up, and avoids extra transaction fees. Other reliable options include Stripe and Razorpay for Indian businesses. Shopify supports over 100 payment gateways worldwide, offering flexibility and security for global transactions. Choosing the right Shopify payment gateway enhances user experience and checkout success.